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Human PDGF R alpha/PDGFRA (His-Avi Tag)
Description
Human PDGF R alpha/PDGFRA (His-Avi Tag)PDGF R alpha (platelet derived growth factor receptor alpha) is a type I transmembrane glycoprotein in the class III subfamily of receptor tyrosine kinases (RTK). Within the ECD, human PDGF R alpha shares 85%, 83%, 95%, 93%, and 88% aa sequence identity with mouse, rat, equine, canine and bovine PDGF R alpha respectively. PDGF R alpha autophosphorylates upon dimerization, activating signaling cascades in PI 3 kinase Ras MAP kinase, and PLC gamma
QFINDAETEL MMSKLPLENP VVLNSFHFAA DCCTSYISQS IPCSLMKSYF ETSSECSKPG VIFLTKKGRQ VCAKPSGPGV QDCMKKLKPY SI
the protein migrates to 42-52 kDa based on Tris-Bis PAGE result
inhibits the branching of prostate epithelium
The extracellular domain of human Fc gamma RIIA shares approximately 90% amino acid sequence homology with human Fc gamma RIIB and Fc gamma RIIC
the control of impurities in intermediate processes
These receptor proteins play a role in important processes such as cell division
and the microbeads are evenly distributed in the buffer
EPS8L3 promotes hepatocellular carcinoma proliferation and metastasis by modulating EGFR dimerization and internalization
40303_MSDS_HB250721
It shows considerable glycosylation
product-specific manufacturing processes and analytical methods compliant with ISO 13485 and GMP requirements
Neurturin is expressed in both neuronal and non-neuronal tissues
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Ships within 48 hours · Estimated delivery Jul 13 - Jul 18
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